OSA / CLINICAL PHENOME
How is obstructive sleep apnea associated with the clinical phenome?
Explore adjusted relationships between OSA severity and diseases, laboratory patterns, medication fills, EHR-derived behaviors, procedures, and healthcare use in a sleep-clinic referral cohort.
Results identify the analysis family and coding system before opening evidence.
Two views of disease
Start with the scientific question
01→02→
Existing diagnoses
Prevalence PheDAS
Odds ratios across 1,700+ PheCodesNew diagnoses during follow-up
Incidence PheDAS
Cause-specific hazard ratios across 1,000+ PheCodesSurvival analysis
Explore incidence curves →Trace cumulative incidence after index
Explore Aalen–Johansen curves for FDR-selected incident outcomes by OSA severity or recorded CPAP usage.
Atlas index
One exposure, seven clinical lenses
AnalysisQuestionPrimary measureStatus
Interpret within the cohort.
“None” means AHI <5 among referred adults with sleep studies—not a population control. These results support hypothesis generation; they do not estimate population OSA prevalence or establish causality.
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