OSA / CLINICAL PHENOME

How is obstructive sleep apnea associated with the clinical phenome?

Explore adjusted relationships between OSA severity and diseases, laboratory patterns, medication fills, EHR-derived behaviors, procedures, and healthcare use in a sleep-clinic referral cohort.

Two views of disease

Start with the scientific question

01

Existing diagnoses

Prevalence PheDAS

Odds ratios across 1,700+ PheCodes
02

New diagnoses during follow-up

Incidence PheDAS

Cause-specific hazard ratios across 1,000+ PheCodes
Survival analysis

Trace cumulative incidence after index

Explore Aalen–Johansen curves for FDR-selected incident outcomes by OSA severity or recorded CPAP usage.

Explore incidence curves →
Atlas index

One exposure, seven clinical lenses

AnalysisQuestionPrimary measureStatus
PheDAS Which diseases are already present?ORResearch preview
Incidence PheDAS Which diseases arise during follow-up?HRResearch preview
LabWAS How do laboratory values and ordering differ?β / OR / IRRArchived snapshot
MedWAS Which medication classes are filled?ORArchived snapshot
BehWAS How do EHR-derived behaviors differ?OR / βPreliminary
ProcWAS How do procedure rates differ?IRRArchived snapshot
UtilWAS How does healthcare use differ?OR / IRRReview needed
Interpret within the cohort.

“None” means AHI <5 among referred adults with sleep studies—not a population control. These results support hypothesis generation; they do not estimate population OSA prevalence or establish causality.

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